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Articles by Charles-Schoeman C
Relationship Between Paraoxonase-1 Genotype and Activity, and Major Adverse Cardiovascular Events and Malignancies in Patients with Rheumatoid Arthritis Receiving Tofacitinib - PubMed
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Safety profile of upadacitinib in patients at risk of cardiovascular disease: integrated post hoc analysis of the SELECT phase III rheumatoid arthritis clinical programme - PubMed
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Assessment of antibody levels to SARS-CoV-2 in patients with idiopathic inflammatory myopathies receiving treatment with intravenous immunoglobulin
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Triple therapy, lower RA disease activity linked to lower cholesterol
Triple therapy with methotrexate, sulfasalazine and hydroxychloroquine and reduced disease activity from baseline was associated with lower total, high-density lipoprotein and low-density lipoprotein cholesterol levels after 2 years compared with patients who did not receive triple therapy, according to recently published data. Researchers studied data from a subset of 459 patients in the Treatment of Early Aggressive Rheumatoid Arthritis (TEAR) trial.
Decreased disease activity in patients with RA may improve cholesterol profile
A decrease in disease activity with either methotrexate plus etanercept or triple therapy with methotrexate, sulfasalazine and hydroxychloroquine concomitantly was associated with an increase in HDL levels, lower LDL levels and a lower total cholesterol-to-HDL levels, according to recently published research. The same effects were not observed with methotrexate monotherapy.
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