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eLife Assessment This important study shows that an odorant that is typically thought of as a repellent actually activates both attractant and repellent olfactory neurons in Caenorhabditis elegans. Convincing evidence is provided that nematode worms can integrate signals in different sensory pathways to drive different behavioral responses to the same cue. These findings will be of interest to scientists interested in combinatorial coding in sensory systems.
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