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Introduction Prostate adenocarcinoma (PRAD) is the most common malignancy in males, with its incidence strongly correlated with advancing age (1). In 2020, an estimated 1.4 million new cases of prostate cancer were diagnosed worldwide, contributing to a growing public health burden, particularly in regions with aging populations (1). Radical prostatectomy or radiation therapy are the main curative treatment options for prostate cancer.
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