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Abstract Chronic wound infections are sustained by dynamic three-dimensional (3D) biofilm cycles involving maturation, dispersal, and recolonisation, yet existing in vitro models fail to reproduce these temporal and structural complexities. Here, we report a strategy that co-assembles a designed protease-inhibitory peptide amphiphile (PA) with patient-derived wound fluid (WF) to reconstruct the complete biofilm life cycle in vitro.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
