1. Introduction One of the major factors causing reduced developmental capacity of aged porcine oocytes is the induction of oxidative stress during oocyte aging [1], as oxidative stress gives rise to a series of cascade reactions that negatively affect oocyte quality, such as morphological (spontaneous oocyte activation and oocyte death), cellular (spindle formation and cortical granule migration anomalies), and molecular (mitochondrial dysfunction and apoptosis) changes [2].
