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Chiara Mizzotti

As seen in: Nature
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Articles by Chiara Mizzotti

ARABIDOPSIS Bsister and SEEDSTICK MADS-box transcription factors modulate maternal nutrient flow for seed development in Arabidopsis

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By Camilla Banfi, Chiara Astori, Chiara Mizzotti, Rosario Vega-León, Giulia Leo, Ueli Grossniklaus, Matthew Tucker, Fabrizio Araniti, Riccardo Aiese Cigliano, Walter Sanseverino, Ignacio Ezquer, Jose M. Muino, Kerstin Kaufmann, Maurizio Di Marzo, Lucia Colombo, Nicola Babolin, Carlotta Nardi
| Nature Verified
Abstract Successful seed development in Angiosperms depends on the coordinated transport and allocation of sugars from maternal tissues to the developing embryo and endosperm. In Arabidopsis thaliana, ovules function as carbohydrate sink organs, accumulating starch in both gametophytic and sporophytic domains prior to fertilization. During early embryogenesis, the stored starch is then mobilized.
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SPOROCYTELESS/NOZZLE cooperates with MADS-domain transcription factors to regulate an auxin-dependent network controlling Megaspore-Mother-Cell differentiation | Nature Communications

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By Alex Cavalleri, Silvia Manrique, Cezary Smaczniak, Kerstin Kaufmann, Chiara Mizzotti
| Nature Verified
Abstract The formation of the female gamete is a complex developmental process that begins with the differentiation of the Megaspore Mother Cell (MMC) within the ovule. SPOROCYTELESS/NOZZLE (SPL/NZZ) is the principal regulator of the MMC formation, as mutations in the SPL/NZZ gene lead to the failure of the MMC differentiation. Nonetheless, the SPL/NZZ-dependent regulatory pathway governing the MMC development remains largely unknown.
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