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Loading metrics Open Access Peer-reviewed Research Article Julie Takagi, Sheena D. Singh-Babak, Matthew B. Lohse, Chiraj K. Dalal , Alexander D. Johnson Julie Takagi, Sheena D. Singh-Babak, Matthew B. Lohse, Chiraj K. Dalal, Alexander D.
High throughput gene expression profiling of yeast colonies with microgel-culture Drop-seq Yeasts can be engineered into “living foundries” for non-natural chemical production by reprogramming their genome using a synthetic biology “design-build-test” cycle. While methods for “design” and “build” are scalable and efficient, “test” remains a labor-intensive bottleneck, limiting the effectiveness of the genetic reprogramming results.
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