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Articles by Christine Tedijanto
Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period
What happens next? Four months into the severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) outbreak, we still do not know enough about postrecovery immune protection and environmental and seasonal influences on transmission to predict transmission dynamics accurately. However, we do know that humans are seasonally afflicted by other, less severe coronaviruses. Kissler et al.
Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period
Abstract It is urgent to understand the future of severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) transmission. We used estimates of seasonality, immunity, and cross-immunity for betacoronaviruses OC43 and HKU1 from time series data from the USA to inform a model of SARS-CoV-2 transmission. We projected that recurrent wintertime outbreaks of SARS-CoV-2 will probably occur after the initial, most severe pandemic wave.
Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period
Abstract It is urgent to understand the future of severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) transmission. We used estimates of seasonality, immunity, and cross-immunity for betacoronaviruses OC43 and HKU1 from time series data from the USA to inform a model of SARS-CoV-2 transmission. We projected that recurrent wintertime outbreaks of SARS-CoV-2 will probably occur after the initial, most severe pandemic wave.
Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period
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Social distancing strategies for curbing the COVID-19 epidemic
Abstract The SARS-CoV-2 pandemic is straining healthcare resources worldwide, prompting social distancing measures to reduce transmission intensity. The amount of social distancing needed to curb the SARS-CoV-2 epidemic in the context of seasonally varying transmission remains unclear. Using a mathematical model, we assessed that one-time interventions will be insufficient to maintain COVID-19 prevalence within the critical care capacity of the United States.
Projecting the transmission dynamics of SARS-CoV-2 through the post-pandemic period
Abstract There is an urgent need to project how transmission of the novel betacoronavirus SARS-CoV-2 will unfold in coming years. These dynamics will depend on seasonality, the duration of immunity, and the strength of cross-immunity to/from the other human coronaviruses. Using data from the United States, we measured how these factors affect transmission of human betacoronaviruses HCoV-OC43 and HCoV-HKU1.
Potential impact of outpatient stewardship interventions on antibiotic exposures of common bacterial pathogens
Abstract The relationship between antibiotic stewardship and population levels of antibiotic resistance remains unclear. In order to better understand shifts in selective pressure due to stewardship, we use publicly available data to estimate the effect of changes in prescribing on exposures to frequently used antibiotics experienced by potentially pathogenic bacteria that are asymptomatically colonizing the microbiome. We quantify this impact under four hypothetical stewardship strategies.
Resistance diagnostics as a public health tool to combat antibiotic resistance: A model-based evaluation
Loading metrics Open Access Peer-reviewed Research Article Subject Areas ? For more information about PLOS Subject Areas, click here. We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help! Opportunistic pathogens Antibiotics Antibiotic resistance Drug therapy Pathogens Bacterial pathogens Diagnostic medicine Drug discovery
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