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Christopher Rowe

As seen in: Nature, JAMA: Journal of the American Medical Association, Bryn Mawr Classical Review
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Articles by Christopher Rowe

Exploring the relationship between methylation of the cortisol receptor genes and brain and cognitive outcomes in individuals with elevated amyloid-β

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By Ayeisha Milligan Armstrong, Lidija Milicic, Michael Vacher, Eleanor K. O’Brien, Vincent Doré, Pierrick Bourgeat, Rosita Shishegar, Ying Xia, Christopher Rowe, Victor L. Villemagne, Paul Maruff, Colin Masters, Giuseppe Verdile, Simon Laws, David Groth, Tenielle Porter, Lifestyle study, Shane Fernandez
| Nature Verified
Abstract Chronic psychological stress has been implicated as a risk factor for Alzheimer’s disease (AD), potentially through cortisol-mediated acceleration of disease progression. However, the molecular pathways underlying this relationship remain poorly understood. Epigenetic regulation of the glucocorticoid and mineralocorticoid receptor genes (NR3C1 and NR3C2), which encode receptors for cortisol, may play an important role, but has not been examined in relation to AD progression.
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Bryn Mawr Classical Review

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By Christopher Rowe, Brad Inwood
| Bryn Mawr Classical Review
Preview In 2017, when presenting his text-in-progress of book 2 of the Eudemian Ethics to the Symposium Aristotelicum in Athens, the late Christopher Rowe said, only half in jest, that he hoped to live long enough to finish his new critical text of the EE, as previous editors, notably Richard Walzer, had not been able to do. Rowe got his wish, and his splendid Oxford Classical Text of this problematic Aristotelian work appeared in 2023, two years before his death at the age of 81.
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Are Blood Tests for Alzheimer Disease Ready for Prime Time?

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By Stephen Salloway, Christopher Rowe, Jeffrey Burns
| JAMA: Journal of the American Medical Association Verified
This is a transformative time for patients with Alzheimer disease. Alzheimer disease is increasingly viewed as a treatable condition and managed like other major chronic diseases, such as heart disease and cancer. Management of Alzheimer disease includes early diagnosis with molecular confirmation, disease-modifying treatments that are initiated early in the disease course, better risk reduction and prevention strategies, and improved coordination of care.
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