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Christopher Shi

As seen in: Wiley Online Library, Texas Medical Center
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Articles by Christopher Shi

Escalated-Dose Radiotherapy for Unresected Locally Advanced Pancreatic Cancer: Patterns of Care and Survival in the United States

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By Christopher Shi, Brian De, Suyu Liu, Marcus A. Florez
| Texas Medical Center
INTRODUCTION: With locally advanced pancreatic cancer (LAPC), uncontrolled local tumor growth frequently leads to mortality. Advancements in radiotherapy (RT) techniques have enabled conformal delivery of escalated-dose RT (EDR), which may have potential local control and overall survival (OS) benefits based on retrospective and early prospective studies. With evidence for EDR emerging, we characterized the adoption of EDR across the United States and its associated outcomes.
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Escalated‐dose radiotherapy for unresected locally advanced pancreatic cancer: Patterns of care and survival in the United States

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By Christopher Shi, Brian De, Suyu Liu, Marcus A. Florez
| Wiley Online Library Verified
1 INTRODUCTION Locally advanced pancreatic cancer (LAPC) accounts for approximately 80% of pancreatic cancer cases and is associated with a poor prognosis, with median survival of 13–24 months.1, 2 Mortality for patients with LAPC is driven by both early metastatic spread and uncontrolled local growth; an estimated 30% of patients with LAPC die with local progression alone, and an additional 10%–25% experience both local progression and distant spread before death.3, 4 Treatments that confer...
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