Start-ups are the heart of innovation in the pharmaceutical biotech industry. In drug discovery and development, the early steps are crucial and have the potential to determine whether the start-up will make it and develop a life-altering cure. The Hive, an initiative for biotech and pharmaceutical start-up firms, was designed to empower early-stage development and generate stories that offer lessons on how R&D teams can overcome the bottlenecks and challenges that arise in the process.