Introduction The early post-acute stroke period is characterized by spontaneous recovery that occurs within a narrow time window, during which animals and humans also exhibit heightened responsiveness to training (Biernaskie et al., 2004; Dromerick et al., 2021). This time-limited enhanced capacity for recovery has been attributed to a transient increase in plasticity within the peri-infarct region, particularly through elevated expression of long-term potentiation (LTP).