Abstract To report the pain relief and procedure-related outcomes of percutaneous cryoablation (CA) of painful endometriosis deposits in unusual anatomic locations. A retrospective search of institutional radiological information system identified a total of 15 patients (median age 35.5 years; interquartile ranges—IQR 33–38). Patients and lesions specific data as well as procedural and follow-up information were collected, analyzed, and presented using descriptive statistical methods.