Prostate cancer is a high-incidence male cancer that progresses to metastatic disease in a subset of diagnosed cases. Early detection of high-risk disease is a key translational challenge and if successful will reduce overtreatment while potentially improving the outcomes for those patients most in need of early interventions. There are many challenges that need to be surmounted to achieve this translational outcome, not least the fact that prostate cancer is a multi-focal disease.
