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A reactant B product 1D one-dimensional (model) 2D two-dimensional (model) 1 Introduction Strongly exothermic heterogeneous catalytic reactions are challenging due to heat-transfer limitations and the risk of thermal runaway. Therefore, wall-cooled fixed-bed reactors are employed to ensure safe reactor operations. Examples are Fischer–Tropsch synthesis, methanation, or methanol synthesis, often conducted in multi-tubular reactors cooled by boiling water.
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