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Cristian A.W.V on Muck Rack

Cristian A.W.V

As seen in: Cancer Research
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Articles by Cristian A.W.V

Development of a [89Zr]Zr-labeled Human Antibody using a Novel Phage-displayed Human scFv Library

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By Cristian A.W.V, Jong Hee, Young Ah
| Cancer Research Verified
Tax-interacting protein 1 (TIP1) is a cancer-specific radiation-inducible cell surface antigen that plays a role in cancer progression and resistance to therapy. This study aimed to develop a novel anti-TIP1 human antibody for noninvasive PET imaging in patients with cancer. A phage-displayed single-chain variable fragment (scFv) library was created from healthy donors’ blood. High-affinity anti-TIP1 scFvs were selected from the library and engineered to human IgG1.
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Development of a [89Zr]Zr-labeled human antibody using a novel phage-displayed human scFv library

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By Cristian A.W.V, Jong Hee, Young Ah
| Cancer Research Verified
Purpose: Tax-interacting protein 1 (TIP1) is a cancer-specific radiation-inducible cell surface antigen that plays a role in cancer progression and resistance to therapy. This study aimed to develop a novel anti-TIP1 human antibody for noninvasive PET imaging in cancer patients. Experimental Design: A phage-displayed scFv library was created from healthy donors’ blood. High-affinity anti-TIP1 scFvs were selected from the library and engineered to human IgG1.
Open in Who Shared Issue with article?
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