Auxiliary Syntheses of MPC Structures The properties of the underlying stereogenic units in rotaxanes and catenanes feeds directly into methods for their synthesis. (37) For example, if the axle or macrocycle components of an MPC rotaxane are disconnected the resulting components are always achiral ( Scheme 2 a). Thus, additional chiral information needs to be included in the forward synthesis if we are to avoid producing a racemic mixture of enantiomeric products. Scheme 2 Scheme 2.
