The authors have declared no competing interest. PG is a Chan Zuckerberg Biohub investigator. DF is supported by the Gerhard C. Starck Foundation. MVK is supported by National Institutes of Health (NIH) grant R00DA051534. EB is supported by NIH grants R01AI127250 and R01HD104835. SHN is supported by the Robert Woods Johnson Foundation. TB is supported by NIH grant R01CA228147 and by the California Environmental Protection Agency's Office of Environmental Health Hazard Assessment (#21-E0018).