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Abstract Umbilical vessel closure after birth prevents hemorrhage but limits the time window for large-bore umbilical cannulation required for artificial placenta support. This review synthesizes physiologic triggers, vasoactive pathways, and vessel-wall specializations that drive rapid postnatal occlusion and highlights engineering-relevant targets to prolong functional patency.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
