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Abstract Purpose: Observational associations between statin exposure and mortality in sepsis may be distorted by immortal time bias and covariate timing. We reassessed this association using time-updated exposure and complementary landmark analyses in MIMIC-IV. Methods: Adults with sepsis in MIMIC-IV version 3.1 were followed from ICU admission for 28-day all-cause mortality.
Abstract The prognostic value of postoperative chemotherapy for non-metastatic right-sided colon neuroendocrine carcinoma (RCNEC) remains unclear. This study aimed to evaluate its association with survival outcomes and to develop a prognostic nomogram for surgically treated RCNEC patients.
Abstract Intratumoral heterogeneity (ITH) is a critical factor associated with treatment failure and disease relapse in hepatocellular carcinoma (HCC). However, decoding ITH in a noninvasive and comprehensive manner remains a notable challenge. In this study involving 851 patients from five centers, we developed a noninvasive prognostic classification for ITH using radiomics based on multisequence MRI, termed radiomics ITH (RITH) phenotypes.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
