Vaccines and Antiviral Agents David-Alexandre Gross, Alexandre Ghenassia, Laurent Bartolo, Dominique Urbain, Sofia Benkhelifa-Ziyyat, Stéphanie Lorain, Jean Davoust, Pascal Chappert Rozanne M. Sandri-Goldin, Editor DOI: 10.1128/JVI.01334-18 ABSTRACT A key aspect to consider for vaccinal protection is the induction of a local line of defense consisting of nonrecirculating tissue-resident memory T cells (TRM), in parallel to the generation of systemic memory CD8+ T cell responses.