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AUC area under the curve CAG cytosine-adenine-guanine COM clinical outcome measures DTI diffusion tensor imaging FA fractional anisotropy FARS ADL Friedreich's Ataxia Rating Scale Activities of Daily Living FBA fixel-based analysis FC fiber cross-section FD fiber density FDC combined measure factoring the effects of fiber density and cross-section FDR false discovery rate FOD fiber orientation distribution ICP inferior cerebellar peduncle M1 primary motor cortex MCP middle cerebellar peduncle...
Abstract Objective measures of disease progression are critically needed in research on Parkinson’s disease (PD) and atypical Parkinsonism but may be hindered by both practicality and cost. The Purdue Pegboard Test (PPT) is objective, has high test-retest reliability, and has a low cost.
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