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Abstract Abdominal aortic aneurysms (AAAs) are characterized by progressive extracellular matrix (ECM) degradation and inflammation of the aortic wall. 2-Hydroxypropyl-β-cyclodextrin (cyclodextrin) has shown potential in attenuating AAA progression via activation of transcription factor EB. This study evaluated whether molecular magnetic resonance imaging (MRI) enables non-invasive monitoring of therapeutic effects in a murine AAA model.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.