1 INTRODUCTION Agricultural pesticides have been used worldwide to control pests and diseases, addressing severe challenges that once led to catastrophic events, such as The Great Famine in 1840s caused by potato blight and the Cotton Boll Weevil Infestation in 1910s due to the weevil population explosion.1, 2 The introduction of pesticides marked a significant turning point, enhancing food security through effective pest control.3-5 However, the transition to pesticide-centric approaches has...