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Articles by David M. A
Apraxia phenotypes and frontotemporal lobar degeneration - Journal of Neurology
Abstract Apraxia has been identified in all clinical forms of frontotemporal lobar degeneration (FTLD). The characteristics of apraxia symptoms and their underlying cognitive/motor basis are not fully understood. This study investigated apraxia in pathological subtypes of FTLD. The study constituted a retrospective review of 115 pathologically confirmed cases of FTLD from a single cognitive neurology centre.
Distinct tau folds initiate templated seeding and alter the post-translational modification profile
PDF Split View Article contents Figures & tables Video Audio Supplementary Data Airi Tarutani , Distinct tau folds initiate templated seeding and alter the post-translational modification profile, Brain, 2023;, awad272, https://doi.org/10.1093/brain/awad272 Close tauopathy, tau, post-translational modifications, templated seeding, strains Accepted manuscripts are PDF versions of the author’s final manuscript, as accepted for publication by the journal but prior to copyediting or typesetting.
Corrigendum: The Potential of Functional Near-Infrared Spectroscopy-Based Neurofeedback-A Systematic Review and Recommendations for Best Practice
In the original review article, we miscalculated the statistical power and sensitivity of the included studies which led to an overestimation of power and sensitivity. The miscalculations arose from an easy-to-miss default option for repeated measures (mixed) ANOVAs in the statistical software program GPower (Faul et al., 2007), which co-author (RTT) became aware of after our review was published.
Structure-based classification of tauopathies - Nature
Abstract The ordered assembly of tau protein into filaments characterizes several neurodegenerative diseases, which are called tauopathies. It was previously reported that, by cryo-electron microscopy, the structures of tau filaments from Alzheimer’s disease1,2, Pick’s disease3, chronic traumatic encephalopathy4 and corticobasal degeneration5 are distinct. Here we show that the structures of tau filaments from progressive supranuclear palsy (PSP) define a new three-layered fold.
Comparison of Common and Disease-Specific Post-translational Modifications of Pathological Tau Associated With a Wide Range of Tauopathies
Introduction Neurodegenerative tauopathies are characterized by cytoplasmic aggregates of hyperphosphorylated tau protein (Goedert et al., 1992; Buee et al., 2000; Lee et al., 2001).
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