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Articles by de Bock
“It cannot depend solely on the parents”—professionals’ perspectives on patient journeys of children with chronic conditions across health and social care in Germany
Wisk LE, Sharma N (2025) Prevalence and trends in pediatric-onset chronic conditions in the United States, 1999–2018. Acad Pediatr 25:102810. https://doi.org/10.1016/j.acap.2025.102810 Article PubMed Google Scholar Lancet T (2008) More evidence needed for chronic conditions in children. Lancet 372:1708.
Young women with (pre)malignant cervical disease in northern Netherlands: what characterises them – A population-based cohort study
Background Little is known on (pre)malignant cervical disease in women below the age of population-based screening (PBS). The aim of this study was to evaluate the occurrence of (pre)malignant cervical disease and related sociodemographic characteristics in women who are tested and/or referred by the GP before reaching the eligible age (30 years) for participation in the first round of PBS for cervical cancer in the northern Netherlands.
Fully closed-loop systems: can people with type 1 diabetes just do it? Insights from open-source systems - Diabetologia
Anandhakrishnan A, Hussain S (2024) Automating insulin delivery through pump and continuous glucose monitoring connectivity: maximizing opportunities to improve outcomes. Diabetes Obes Metab 26(S7):27–46. https://doi.org/10.1111/dom.15920 Article CAS PubMed PubMed Central Google Scholar Braune K, Lal RA, Petruželková L et al (2022) Open-source automated insulin delivery: international consensus statement and practical guidance for health-care professionals. Lancet Diabetes Endocrinol 10(1):58–74.
Robustness and uncertainty: two complementary aspects of the reliability of the predictions of a classifier
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Australasian periprocedural guideline for children and adolescents with diabetes mellitus
General considerations We have provided pre-procedural checklists for caregivers for children and adolescents with diabetes (appendix A) and HCPs professionals (appendix B). The patient facing checklist (Appendix A) should be provided in advance as able (elective surgery for example), to give the family time to ask questions and implement the plan.
Titin Modulation and Left Ventricular Remodelling in Chronic Primary Mitral Regurgitation
ORIGINAL RESEARCH article LL Lobke L Pype 1,2 SL Sven L. Van Laer 1,2 IR Inez Rodrigus 1,2 CM Caroline M. Van De Heyning 1,2 NH Nazha Hamdani 3 EM Emeline M Van Craenenbroeck 1 1. Antwerp University Hospital, Antwerp, Belgium 2. Universiteit Antwerpen, Antwerp, Belgium 3.
Clinical validation of a three-marker methylation panel to detect CIN3+ in vaginal self-samples in the Dutch population-based screening programme - Clinical Epigenetics
Abstract The use of vaginal self-sampling for cervical cancer screening is promising and increasing. However, triage cytology cannot be performed on vaginal self-sampling material after a high-risk human papilloma virus (hrHPV)-positive result. In our recent discovery study, we identified a three-marker panel with high sensitivity (82%) and specificity (74%) for CIN3 or worse (CIN3+).
Dopaminergic manipulation modulates frequency-specific EEG connectivity patterns: Evidence from a single dose drug challenge study
ORIGINAL RESEARCH article Front. Neurosci. Sec.
Increased skin autofluorescence predicts future cancer development - BMC Cancer
A total of 77,961 Lifelines participants were considered free of cancer at the baseline examination. This included 75,678 participants without diabetes (58% were females, 42% were males, mean ± sd age 43 ± 12 years) and 2,283 with type 2 diabetes (47% were females, 53% were males, mean ± sd age 56 ± 12 years). The median follow-up time was 11.5 years, with an interquartile range of 10.5–12.6 years.
Ensemble learning for operations research and business analytics - Annals of Operations Research
Abstract This paper introduces the special issue on Ensemble Learning for Operations Research and Business Analytics. Its main purpose is to provide summaries for the 14 contributing research papers that were accepted for inclusion in this special issue. We first define an updated and extended taxonomy of ensemble learner architectures to characterize and differentiate ensemble learning algorithms.
The effect of hrHPV prevalence on cervical cancer screening strategies: a cost-effectiveness study of Bangladesh - BMC Public Health
This cost-effectiveness evaluation study was performed from a health care system perspective, to objectively account for all costs incurred by either the health care facility, the patients, as well as other funding sources [15]. The micro-simulation Markov model “SiMCerC was used in this study (Fig. 1) [16]. This model was originally developed to simulate the cervical cancer screening process for the Dutch population. The model simulated the life course of 100,000 women from birth to death.
[2410.09055] Geospatial Road Cycling Race Results Data Set
arXiv:2410.09055 (cs) View PDF Subjects: Computers and Society (cs.CY); Machine Learning (cs.LG) Cite as: arXiv:2410.09055 [cs.CY] (or arXiv:2410.09055v1 [cs.CY] for this version) https://doi.org/10.48550/arXiv.2410.09055 Submission history From: Bram Janssens [ view email] [v1] Thu, 26 Sep 2024 13:35:14 UTC (1,606 KB) Bibliographic Tools Bibliographic Explorer Toggle Bibliographic Explorer () Litmaps Toggle Litmaps (What is Litmaps?) scite.ai Toggle scite Smart Citations (What are Smart...
Results from a synthetic model of the ITER XRCS-Core diagnostic based on high-fidelity x-ray ray tracing
Citation N. A. Pablant, Z. Cheng, M. O’Mullane, L. Gao, R. Barnsley, M. N. Bartlett, M. Bitter, E. Bourcart, G. V. Brown, M. De Bock, L. F. Delgado-Aparicio, C. Dunn, A. J. Fairchild, N. Hell, K. W. Hill, J. Klabacha, F. Kraus, D. Lu, P. B. Magesh, S. Mishra, M. Sánchez del Río, R. Tieulent, Y. Yakusevich; Results from a synthetic model of the ITER XRCS-Core diagnostic based on high-fidelity x-ray ray tracing. Rev. Sci. Instrum. 1 August 2024; 95 (8): 083517. https://doi.org/10.1063/5.0219328 Download citation file:
Extending choice assessments to choice functions: An algorithm for computing the natural extension
arXiv:2407.21164 (cs) View PDF Comments: Subjects: Artificial Intelligence (cs.AI); Probability (math.PR) MSC classes: 68T37, 60A99 Cite as: arXiv:2407.21164 [cs.AI] (or arXiv:2407.21164v1 [cs.AI] for this version) Submission history From: Arne Decadt [ view email] [v1] Tue, 30 Jul 2024 20:10:59 UTC (159 KB) Bibliographic Tools Bibliographic Explorer Toggle Bibliographic Explorer () Litmaps Toggle Litmaps (What is Litmaps?) scite.ai Toggle scite Smart Citations (What are Smart Citations?)...
Field measurements performed on Staghorn fern colonies (Platycerium bifurcatum)
Published June 25, 2024 | Version v1 Dataset Open 1. Victoria University of Wellington This study explores the relationship observed between 'guests' – foreign inhabitants of social colonies – and the density and fecundity of eusocial-like staghorn ferns (Platycerium bifurcatum, Polypodiaceae). Our observations suggest that guests in staghorn colonies have a range of commensal and negative relationships, paralleling those seen in eusocial animal species.
Improved Glycemic Outcomes With Diabetes Technology Use Independent of Socioeconomic Status in Youth With Type 1 Diabetes
Technology use in type 1 diabetes (T1D) is impacted by socioeconomic status (SES). This analysis explored relationships between SES, glycemic outcomes, and technology use. A cross-sectional analysis of HbA data from 2,822 Australian youth with T1D was undertaken. Residential postcodes were used to assign SES based on the Index of Relative Socio-Economic Disadvantage (IRSD). Linear regression models were used to evaluate associations among IRSD quintile, HbA , and management regimen.
Performance evaluation of protocols for Taenia saginata and Ascaris suum egg recovery from the house fly’s gastrointestinal tract and exoskeleton - Parasites & Vectors
Adult house flies were obtained from the stock colony maintained at room temperature under a natural photoperiod in the Laboratory of Foodborne Parasitic Zoonoses, Faculty of Veterinary Medicine (Ghent University, Merelbeke, Belgium). Flies were euthanized by freezing at – 20 °C for 15 min. Taenia saginata proglottids were obtained from Belgian commercial laboratories. Upon arrival, eggs were extracted from the proglottids by gentle maceration using forceps.
Impact of health-related behavioral factors on participation in a cervical cancer screening program: the lifelines population-based cohort - BMC Public Health
This cross-sectional research is nested in the Lifelines cohort, a multidisciplinary, prospective, population-based study using a unique three-generation design to examine the health and health-related behaviors of 167,729 people living in the north of the Netherlands.
Development and validation of a self-regulation scale within the German version of the Early Development Instrument - BMC Pediatrics
The aim of the study was to identify items eligible for SR-measurement within the (G)EDI domains "social competence" and "emotional maturity" by a theory-based selection process, and therefrom develop a GEDI-SR scale and assess its dimensions, psychometric properties and validity. We identified 20 original (G)EDI items eligible for measuring SR. Starting with these 20 items, we used exploratory factor analysis to assess constructs and dimensions using the development dataset.
Following in Banting’s footsteps or straying from the path? Observations from contemporary diabetes innovation
1 Introduction The 100-year anniversary of the discovery of insulin is a timely reminder that altruism is central to the ethos of diabetes management. Indeed, Banting felt it was unethical for a doctor to profit from a discovery that would save lives, leading to the insulin patent being sold to the University of Toronto for a mere $1 (1).
Microbiological profiling and knowledge of food preservation technology to support guidance on a neutropenic diet for immunocompromised patients
1. Introduction Microorganisms are inherently present in food, although the numbers and types of microorganisms may vary depending upon the type and origin of the food, the hygienic practices upon production, processing, and storage, and the food preservation technology applied. Most microorganisms are harmless, many are highly beneficial, some indicate inappropriate handling or cause spoilage, and a few may cause disease.
Urinary albumin excretion and cancer risk: the PREVEND cohort study
Chronic kidney disease (CKD) is defined as abnormalities of kidney structure or function, present for >3 months, with implications for health [1]. It is now generally acknowledged that CKD predisposes for shorter life expectancy, especially because of a link with cardiovascular disease [2]. Cancer is one of the other most common causes of mortality [3]. Accumulating evidence has shown that CKD is associated with a higher risk to develop cancer, especially urinary tract cancer.
Comparison of two frailty screening tools in older patients with colorectal cancer
BMC Geriatrics, May 2023 This is a preview of a remote PDF: https://bmcgeriatr.biomedcentral.com/counter/pdf/10.1186/s12877-023-03974-3 Zhao, Han, Lu, Xinlin, Zheng, Senshuang, Wei, Danmei, Zhao, Lizhong, Wang, Yuan, de Bock, Geertruida H., Lu, Wenli. , BMC Geriatrics, 2023, pp. 1-8, Volume 23, Issue 1, DOI: 10.1186/s12877-023-03974-3
[2302.07412] A theory of desirable things
[Submitted on 15 Feb 2023 ( v1 ), last revised 10 May 2023 (this version, v3)] Title:A theory of desirable things Download a PDF of the paper titled A theory of desirable things, by Jasper De Bock Download PDF Abstract: Inspired by the theory of desirable gambles that is used to model uncertainty in the field of imprecise probabilities, I present a theory of desirable things. Its aim is to model a subject's beliefs about which things are desirable.
[2302.08176] The logic behind desirable sets of things, and its filter representation
arXiv:2302.08176 (math) [Submitted on 16 Feb 2023 (v1), last revised 9 May 2023 (this version, v2)] Download a PDF of the paper titled The logic behind desirable sets of things, and its filter representation, by Gert de Cooman and Arthur Van Camp and Jasper De Bock Download PDF Submission history From: Gert de Cooman [ view email] [v1] Thu, 16 Feb 2023 09:45:21 UTC (49 KB) [v2] Tue, 9 May 2023 14:54:41 UTC (50 KB) Bibliographic Tools Bibliographic Explorer Toggle Bibliographic Explorer ()...
Influenza season influence on outcome of new nodules in the NELSON study
Scientific Reports, Apr 2023 This is a preview of a remote PDF: https://www.nature.com/articles/s41598-023-33672-4.pdf Lancaster, H. L., Heuvelmans, M. A., de Bock, G. H., Du, Y., Mohamed Hoesein, F. A. A., Nackaerts, K., Walter, J. E., Vliegenthart, R., Oudkerk, M.. , Scientific Reports, DOI: 10.1038/s41598-023-33672-4
Frontiers | User experiences during the transition to calibration-free sensors with remote monitoring while using automated insulin delivery - a qualitative study
Highlights 1. What is already known? ● Automated Insulin delivery devices(AID) can revolutionize type 1 diabetes management and have evolved to incorporate calibration free/reduced sensors, whose impact on user experience in Medtronic devices is unknown. 2. What this study adds? ● AID with calibration-free CGM was perceived to offer improved system stability, users reported a high degree of trust in the new device, improved quality of life with reduced diabetes care burden.
Shaping the brain vasculature in development and disease in the single-cell era
Nature Reviews Neuroscience, Apr 2023 This is a preview of a remote PDF: https://www.nature.com/articles/s41583-023-00684-y.pdf Wälchli, Thomas, Bisschop, Jeroen, Carmeliet, Peter, Zadeh, Gelareh, Monnier, Philippe P., De Bock, Katrien, Radovanovic, Ivan. , Nature Reviews Neuroscience, DOI: 10.1038/s41583-023-00684-y
3′‐end mRNA processing within apicomplexan parasites, a patchwork of classic, and unexpected players
1 INTRODUCTION In eukaryotic cells, transcription by RNA polymerase II (Pol II) first generates a pre-mRNA that undergoes several modification steps, including 5′-end capping, internal nucleotide modifications, splicing, and 3′-end processing. All of these processes occur co-transcriptionally and within a limited time frame, resulting in kinetic coupling of most of these processes (reviewed by David Bentley—Bentley, 2014).
Exploiting time-varying RFM measures for customer churn prediction with deep neural networks
Annals of Operations Research, Mar 2023 This is a preview of a remote PDF: https://link.springer.com/content/pdf/10.1007/s10479-023-05259-9.pdf Mena, Gary, Coussement, Kristof, De Bock, Koen W., De Caigny, Arno, Lessmann, Stefan. , Annals of Operations Research, 2023, pp. 1-23, DOI: 10.1007/s10479-023-05259-9
Unusual PDGFRB fusion reveals novel mechanism of kinase activation in Ph-like B-ALL
Leukemia, Feb 2023 This is a preview of a remote PDF: https://www.nature.com/articles/s41375-023-01843-x.pdf Sadras, Teresa, Jalud, Fatimah B., Kosasih, Hansen J., Horne, Christopher R., Brown, Lauren M., El-Kamand, Sam, de Bock, Charles E., McAloney, Lachlan, Ng, Ashley P., Davidson, Nadia M., Ludlow, Louise E. A., Oshlack, Alicia, Cowley, Mark J., Khaw, Seong L., Murphy, James M., Ekert, Paul G.. , Leukemia, DOI: 10.1038/s41375-023-01843-x
Do family characteristics contribute to a socioeconomic gradient in overweight in early childhood? – Single mediation analyses of data from German preschool children
Do family characteristics contribute to a socioeconomic gradient in overweight in early childhood? – Single mediation analyses of data from German preschool children Children’s overweight is strongly associated with family socioeconomic position (SEP) and family characteristics (FC). There is limited research on the extent to which FC account for a socioeconomic gradient in childhood overweight. This study examined whether FC explain SEP differences in the prevalence of overweight.
Socioeconomic status and diabetes technology use in youth with type 1 diabetes: a comparison of two funding models
Introduction Advanced diabetes technologies including the use of pump therapy and continuous glucose monitoring (CGM) are associated with improved glycaemic outcomes in youth with type 1 diabetes (T1D) (1–5).
The Value of Glycemic Control Prior to Cancer Diagnosis on All-Cause Mortality among Patients with Type 2 Diabetes in Dutch Primary Care
We thank the staff at the Netherlands Comprehensive Cancer Organisation (IKNL) for their invaluable scientific advice and assistance with data collection from the NCR. Doctored Ltd (www.doctored.org.uk) provided editorial services for the final drafts of this manuscript. This work was supported by the Graduate School of Medical Sciences of the University of Groningen and University Medical Center Groningen (PhD position for the first author).
Microbiological profiling and knowledge of food preservation technology to support guidance on a neutropenic diet for immunocompromised patients
Thomas De Bock1*, Liesbeth Jacxsens1, Femke Maes2, Svenya Van Meerhaeghe2, Marina Reygaerts3 and Mieke Uyttendaele1 1Department of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, Belgium 2Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Belgium 3Department of Medical Oncology, Ghent University Hospital, Belgium The final, formatted version of the article will be published soon.
H3K18 lactylation marks tissue-specific active enhancers - Genome Biology
Cell culture All cells were cultured in a humidified incubator at 37°C and 5% CO2. BMDM Bone marrow precursor cells were flushed out of the femur and tibiae bones with a syringe and needle and cultured for 7 days in DMEM, 20% heat-inactivated fetal bovine serum (FBS), 100 U/mL penicillin-streptomycin (P/S; Gibco, 15140122), and 40 ng/ml of recombinant M-CSF (PeproTech, 315-02).
Video-Based Analysis and Reporting of Riding Behavior in Cyclocross Segments
Video-based trajectory analysis might be rather well discussed in sports, such as soccer or basketball, but in cycling, this is far less common. In this paper, a video processing pipeline to extract riding lines in cyclocross races is presented. The pipeline consists of a stepwise analysis process to extract riding behavior from a region (i.e., the fence) in a video camera feed.
BETter insight into PRC2-mutated T-ALL
Skip Nav Destination Lymphoid Neoplasia| November 11, 2021
Diet quality indices and gastrointestinal cancer risk: results from the Lifelines study - European Journal of Nutrition
Abstract Objective To investigate the long-term association between four dietary quality indices and the risk of gastrointestinal (GI) cancer. Methods Baseline details of the dietary intake of participants, assessed by a single food frequency questionnaire from the prospective Lifelines population-based cohort were translated to diet quality scores using several dietary and dietary-lifestyle indices.
Outcome of Quality of Life for Women Undergoing Autologous... : Plastic and Reconstructive Surgery
Breast cancer is recognized as the most frequently diagnosed cancer in female patients worldwide.1 Surgical intervention including mastectomy is considered an integral part of and often is essential to favorable therapeutic outcome2 in many patients.
Suz12 inactivation cooperates with JAK3 mutant signaling in the development of T-cell acute lymphoblastic leukemia
Lymphoid Neoplasia| October 17, 2019 You do not currently have access to this content. Client Account You could not be signed in. Please check your email address / username and password and try again. Email address / Username ? Password
Quality of Life 9 to 13 Years after Autologous or... : Plastic and Reconstructive Surgery
An increasing number of women seek to have their breasts reconstructed following surgery for breast cancer.1 Following mastectomy, breast reconstruction can generally be carried out using two techniques. The first is autologous breast reconstruction, in which the patient’s own body tissue is the principal component to reconstruct the volume and lining of a new breast. The second is alloplastic breast reconstruction, in which breast implants are used for volume reconstruction.
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