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Articles by De Chiara
Functional characterization of GplA (MSMEG-0394) reveals a novel determinant of glycopeptidolipids homeostasis in Mycobacterium smegmatis
Abstract Introduction: Glycopeptidolipids (GPLs) are major constituents of the cell envelope of non-tuberculous mycobacteria (NTM) and play essential roles in colony morphology, surface motility, biofilm formation, antimicrobial susceptibility, and host–pathogen interactions. Although the GPL biosynthetic locus has been extensively characterized, the function of several conserved genes within this cluster remains unresolved.
Molecular tumor board availability and organization in sarcoma referral centers in Italy: are we on the right track?
Abstract Background: With the rapid progress of molecular medicine, new target therapies for solid tumors have become available, leading to the creation of molecular tumor boards (MTBs) designated to evaluate potential individualized treatment options. Unlike other solid or liquid tumors, there is no standard and customized tool to analyze sarcoma. We analyzed the organization of MTB in referral centers for sarcomas treatment in Italy.
Mandibular Response in Class II Division 1 Growing Subjects: Clear Aligners vs. Rapid Maxillary Expansion Therapy. A Controlled Pilot Study
Conflicts of Interest The authors report a funding relationship between themselves and Align Technology. However, Align Technology had no role in the design of the study, in the collection, analyses, or interpretation of data, in the writing of the manuscript, or in the decision to publish the results. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request.
A 3D bioengineered human liver for the study of acute and chronic drug-induced hepatotoxicity and fibrosis
Abstract The liver is frequently exposed to acute and chronic insults that disrupt its function, leading to inflammation, fibrosis, and serious conditions like cirrhosis and hepatocellular carcinoma. Fibrosis, driven by the activation of hepatic stellate cells is a key feature of chronic liver damage. Traditional 2D liver models face limitations in maintaining liver functions and accurately replicating chronic conditions like fibrosis.
Cancer evolution and multi-omic profile of relapsed colorectal liver metastases after treatment - Genome Medicine
Treatment sequencing in metastatic colorectal cancer. Eur J Cancer. 2019;109:70–83. Google Scholar Cervantes A, et al. Metastatic colorectal cancer: ESMO clinical practice guideline for diagnosis, treatment and follow-up. Ann Oncol. 2023;34:10–32. Google Scholar Cervantes A, Martinelli E, ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org.
Golden powers: La concessione, l’estensione e l’escussione del pegno
Ayuda Buscar en la ayuda Buscar en la ayuda Golden powers: La concessione, l’estensione e l’escussione del pegno Autores: Edoardo De Chiara, Angela Ricciardi Localización: Revista Lex Mercatoria, ISSN-e 2445-0936, Nº. 31, 2025, págs.
Igualdad de oportunidades e inclusión laboral en el contexto de la diversidad religiosa: gestión del tiempo para trabajadores musulmanes
Ayuda Buscar en la ayuda Buscar en la ayuda Igualdad de oportunidades e inclusión laboral en el contexto de la diversidad religiosa: gestión del tiempo para trabajadores musulmanes Autores: Gabriella de Chiara Localización: Revista Internacional y Comparada de Relaciones Laborales y Derecho del Empleo, ISSN-e 2282-2313, Vol. 13, Nº. 4 (Relaciones laborales entre precariedad, migración y era digital), 2025, págs.
Anti-nephrin, anti-podocin and anti-Kirrel1 antibodies: biological challenges and clinical implications
The identification of circulating autoantibodies targeting podocyte slit diaphragm proteins—particularly nephrin—has substantially reshaped our understanding of glomerular diseases, especially podocytopathies.
Lactococcus lactis I7 isolated from traditional Italian cheese making: a biotechnological integrated platform - BMC Biotechnology
L. lactis subspecies lactis I7, used in the study, was previously isolated from natural whey starters cultures (it was the initial fermented milk) of cow milk for the production of artisanal cheeses [25]. L. lactis I7 was initially grown in M17 media in exponential growth phase followed by harvesting biomass in fresh sterile M17 media with 20% glycerol and preserving immediately at -80˚C.
Igualdad de género y acceso al mercado laboral.: ¿Qué herramientas para reducir la brecha salarial de género en el contexto europeo? Análisis comparativo entre Italia y España
Ayuda Buscar en la ayuda Buscar en la ayuda Igualdad de género y acceso al mercado laboral.: ¿Qué herramientas para reducir la brecha salarial de género en el contexto europeo? Análisis comparativo entre Italia y España Autores: Gabriella de Chiara Localización: Revista Internacional y Comparada de Relaciones Laborales y Derecho del Empleo, ISSN-e 2282-2313, Vol. 13, Nº. 1, 2025, págs.
Hedgehog and PI3K/Akt/mTOR Signaling Pathways Involvement in Leukemic Malignancies: Crosstalk and Role in Cell Death
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Climate Change, Kidney Health, and Environmentally... : Journal of the American Society of Nephrology
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Single nucleotide polymorphisms associated with wine fermentation and adaptation to nitrogen limitation in wild and domesticated yeast strains
Biological Research, Jul 2023 For more than 20 years, Saccharomyces cerevisiae has served as a model organism for genetic studies and molecular biology, as well as a platform for biotechnology (e.g., wine production). One of the important ecological niches of this yeast that has been extensively studied is wine fermentation, a complex microbiological process in which S. cerevisiae faces various stresses such as limited availability of nitrogen.
A Clinical Workflow for Cost-Saving High-Rate Diagnosis of... : Journal of the American Society of Nephrology
1Nephrology and Dialysis Unit, Meyer Children's Hospital IRCCS, Florence, Italy 2Department of Biomedical, Experimental and Clinical Sciences “Mario Serio,” University of Florence, Florence, Italy 3Medical Genetics Unit, Meyer Children's Hospital IRCCS, Florence, Italy 4IRES Piemonte, Turin, Italy 5Nephrology and Dialysis Unit, Santo Stefano Hospital, Prato, Italy 6Nephrology, Dialysis and Transplantation Unit, Careggi University Hospital, Florence, Italy 7Nephrology and Dialysis Unit,...
Similarities and differences between multivariate patterns of cognitive and socio-cognitive deficits in schizophrenia, bipolar disorder and related risk (pdf) | Paperity
npj Schizophrenia, Feb 2023 This is a preview of a remote PDF: https://www.nature.com/articles/s41537-023-00337-0.pdf Raio, Alessandra, Pergola, Giulio, Rampino, Antonio, Russo, Marianna, D’Ambrosio, Enrico, Selvaggi, Pierluigi, De Chiara, Valerie, Altamura, Mario, Brudaglio, Flora, Saponaro, Alessandro, Semisa, Domenico, Bertolino, Alessandro, Antonucci, Linda A., Blasi, Giuseppe. , npj Schizophrenia, DOI: 10.1038/s41537-023-00337-0
L'immagine, il prezzo del consenso e il risarcimento dell'inquietudine (Nota a Cass., ord. 12 aprile 2022,n.11768)
IdiomacatalàDeutschEnglishespañoleuskarafrançaisgalegoitalianoportuguêsromână
Aborting meiosis allows recombination in sterile diploid yeast hybrids - Nature Communications
Abstract Hybrids between diverged lineages contain novel genetic combinations but an impaired meiosis often makes them evolutionary dead ends. Here, we explore to what extent an aborted meiosis followed by a return-to-growth (RTG) promotes recombination across a panel of 20 Saccharomyces cerevisiae and S. paradoxus diploid hybrids with different genomic structures and levels of sterility.
A Clinical Workflow for Cost-saving High-rate Diagnosis of... : Journal of the American Society of Nephrology
1Nephrology and Dialysis Unit, Meyer University Hospital, Florence, Italy 2Department of Biomedical, Experimental and Clinical Sciences “Mario Serio,” University of Florence, Florence, Italy 3Medical Genetics Unit, Meyer University Hospital, Florence, Italy 4IRES Piemonte, Turin, Italy 5Nephrology and Dialysis Unit, Santo Stefano Hospital, Prato, Italy 6Nephrology, Dialysis and Transplantation Unit, Careggi University Hospital, Florence, Italy 7Nephrology and Dialysis Unit, Cisanello...
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