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Abstract Background: Major depressive disorder (MDD) is characterized by neuroinflammation and neuronal apoptosis, yet effective brain-targeted delivery strategies remain limited. Exosomes represent promising carriers capable of crossing the blood–brain barrier. This study investigated whether engineered exosomes delivering miR-22-3p by modulating the FURIN/HMGB1 axis. Methods: Serum microRNA expression was assessed in patients with MDD.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
