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Articles by Denise Bernhardt
Intrathecal nivolumab in metastatic solid tumors with leptomeningeal disease: dose escalation part of the multicenter IT-PD1/NOA-26 phase 1 trial
Abstract Leptomeningeal metastatic disease (LMD) of solid tumors represents a cancer stage with high unmet therapeutic need. Here we report results from the dose escalation part of a multicenter phase 1 trial investigating intraventricular nivolumab, now continuing in the expansion part. Eligible participants had LMD from tumors with an approval for intraveneous PD1/PDL1 therapy or high tumor mutational burden.
CT-based radiomics for predicting breast cancer radiotherapy side effects
Health 23 hours ago Cancer doctor says most people will say one of four things right before they die tyla.com - Rhiannon Ingle • 23h The oncologist revealed what phrases are most often used by a person on their deathbed For some people, the subject of death is one to be steered well … NHL 22 hours ago Beloved Washington Capitals radio host makes heartbreaking announcement after tragic diagnosis markerzone.com - Daniel Lucente • 22h Washington Capitals host John Walton has made the...
Cancers | Free Full-Text | Liquid Biopsy in Whole Blood for Identification of Gene Expression Patterns (mRNA and miRNA) Associated with Recurrence of Glioblastoma WHO CNS Grade 4
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Cancers | Free Full-Text | Cytoreduction of Residual Tumor Burden Is Decisive for Prolonged Survival in Patients with Recurrent Brain Metastases-Retrospective Analysis of 219 Patients
1. Introduction The prognosis for patients with brain metastases (BMs) has improved due to enhanced medical care and new treatment options in a multidisciplinary setting [1,2,3]. In this context, the role of surgical intervention of primary BMs has already been described [4,5,6]. Nevertheless, surgical resection increasingly fails to achieve local control [7,8,9].
Imaging the WHO 2021 Brain Tumor Classification: Fully Automated Analysis of Imaging Features of Newly Diagnosed Gliomas
Open AccessArticle by 1,†, 2,†, 1, 3, 4,5, 6, 1, 1, 4,5, 1, 4, 3, 7, 1,8 and 1,* 1 Department of Neuroradiology, Klinikum Rechts der Isar, TU Munich, 81675 Munich, Germany 2 Department of Pathology, Klinikum Rechts der Isar, TU Munich, 81675 Munich, Germany 3 Department of Radiation Oncology, Klinikum Rechts der Isar, TU Munich, 81675 Munich, Germany 4 Department of Neurosurgery, Klinikum Rechts der Isar, TU Munich, 81675 Munich, Germany 5 Department of Neurosurgery, University Medical Center...
Sequential and Hybrid PET/MRI Acquisition in Follow-Up Examination of Glioblastoma Show Similar Diagnostic Performance
Open AccessArticle by Julian Ziegenfeuter 1, Claire Delbridge 2, Denise Bernhardt 3, Jens Gempt 4,5, Friederike Schmidt-Graf 6, Michael Griessmair 1, Marie Thomas 1, Hanno S. Meyer 4,5, Claus Zimmer 1, Bernhard Meyer 4, Stephanie E.
Case Report: Disruption of Resting-State Networks and Cognitive Deficits After Whole Brain Irradiation for Singular Brain Metastasis
Introduction In patients with singular brain metastases of primary solid tumors, neurosurgical resection followed by postoperative whole brain radiation therapy (WBRT) was a common therapeutic approach in the recent decades (Patchell et al., 1998; Gaspar et al., 2010).
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