Introduction Gamma delta (γδ) T cells represent a distinct subset of T cells that play a crucial role in immune surveillance and response. Unlike the more common alpha-beta (αβ) T cells, γδ T cells have unique T-cell receptors (TCRs) composed of γ- and δ chains. They are mostly referred to as innate-like T cells, or unconventional T cells, due to their limited TCR diversity, lack of restriction by polymorphic MHC molecules, and recognition of non-classical antigens [1].
