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Articles by Developmental Disabilities
CENTENE CORPORATION REPORTS THIRD QUARTER 2026 RESULTS
-- Third QuarterGAAP Diluted Loss Per Share of $(0.14); Adjusted Diluted Earnings Per Share of $0.58 -- -- Increases 2026 GAAP Diluted EPS Guidance: Greater than $3.46 & Adjusted Diluted EPS Greater than $5.20 -- Increases 2026 full year adjusted diluted EPS guidance by $0.40. Consolidated HBR of 92.7% in the third quarter, better than expectations, driven by the Medicare segment, with Medicaid and Marketplace on track.
Down Syndrome and Alzheimer’s Disease
The Important Connection By Erica K. Salamida Few people realize that Down syndrome and Alzheimer’s disease share an important biological connection. Individuals with Down syndrome face a significantly elevated risk of developing Alzheimer’s disease, with research indicating a lifetime risk exceeding 90%. While Alzheimer’s typically affects people later in life, individuals with Down syndrome often experience Alzheimer’s-related changes in the brain decades before symptoms appear.
A Typology of Work-Related Psychological Wellbeing Among Clergy: The Francis Burnout Inventory
Asendorpf, J. B. (2015). Person-centered approaches to personality. In M. S. Mikulincer, Phillip R. Cooper, M. Lynne Larsen, Randy J. (Ed.), APA handbook of personality and social psychology, Volume 4: Personality processes and individual differences. (pp. 403–424). American Psychological Association. washington https://doi.org/10.1037/14343-018 Asendorpf, J. B., & Denissen, J. J. (2006).
Transdiagnostic child mental health trajectories in Japan: protocol for a nationwide web‑based open cohort study
Background Preventive psychiatry requires longitudinal, transdiagnostic data from before adolescence, yet such data are scarce. We propose a nationwide, digital, open cohort in Japan to track mental health trajectories from birth to late adolescence using multi-informant assessments (caregivers and adolescents) within a transdiagnostic, biopsychosocial framework.
CENTENE CORPORATION REPORTS SECOND QUARTER 2026 RESULTS 6:01 AM EDT 7/28/2026 - Comtex ST. LOUIS, July 28, 2026 /PRNewswire via COMTEX News Network/ -- Second Quarter GAAP Diluted Earnings Per Share of $2.19; Adjusted Diluted Earnings Per Share of $2.51 ---- Increases 2026 GAAP Diluted EPS Guidance: Greater than $3.11 & Adjusted Diluted EPS Greater than $4.80 -- -- Commercial HBR of 79.2%, demonstrating significant year-over-year improvement in profitability.
CENTENE CORPORATION REPORTS FIRST QUARTER 2026 RESULTS 6:00 AM EDT 4/28/2026 - Comtex ST. LOUIS, April 28, 2026 /PRNewswire via COMTEX News Network/ -- First Quarter GAAP Diluted Earnings Per Share of $3.11; Adjusted Diluted Earnings Per Share of $3.37 -- Increases 2026 GAAP Diluted EPS Guidance to Greater than $2.37 & Adjusted Diluted EPS to Greater than $3.40 -- -- Strong first quarter 2026 adjusted diluted EPS of $3.37, approximately $0.50 better than our expectations.
Medical 411: Ehlers-Danlos Syndrome
By Annette Pinder Ehlers-Danlos syndrome (EDS) is a rare group of inherited disorders caused by genetic mutations that affect the body’s ability to make collagen and other proteins, which are important for connective tissue structure and function. Our connective tissues hold parts of our body together, including bones, cartilage, blood vessels, and organs. Different types of EDS have their own characteristics and potential complications.
Have UB Biologists Found the Key to Treating Autism?
By Annette Pinder A drug developed at the University at Buffalo to treat FOXG1 syndrome has been approved by the U.S. Food and Drug Administration (FDA) for clinical trials. The FDA-approved drug, FRF-001, is a viral gene therapy that targets the underlying genetic cause of FOXG1 syndrome, a rare neurodevelopmental disorder characterized by cognitive and physical disabilities and epilepsy.
Stockwatch
2026-02-06 06:00 ET - News Release -- 2025 Full Year GAAP Diluted Loss Per Share of $(13.53); Adjusted Diluted Earnings Per Share of $2.08 -- -- 2026 Adjusted Diluted Earnings Per Share Guidance of Greater than $3.00 -- Consolidated HBR of 94.3% in the fourth quarter of 2025, which includes a Commercial HBR of 95.4% that was 100basis points higher than expectations driven by net out of period items.
Major Lancet Study Finds No Link Between Tylenol and Autism
By Annette Pinder For years, expectant parents have encountered confusing and often alarming headlines suggesting a possible link between acetaminophen, commonly known as Tylenol, and autism. A significant new study published in The Lancet Obstetrics & Gynaecology in January 2026 provides clarity and reassurance. A review of 43 studies involving 2.6 million children on acetaminophen use during pregnancy found no evidence linking Tylenol to autism or other neurodevelopmental disorders.
Toward an idiographic understanding of the role of sleep‐mood dynamics in adolescents' internalizing symptoms
INTRODUCTION Adolescence is a critical developmental period marked by heightened emotional sensitivity and an increased risk for internalizing disorders, such as depression and anxiety (Casey et al., 2008).
Could AI-Powered Handwriting Analysis Help Spot Dyslexia?
By Cory Nealon A new study led by UB explains how AI-powered handwriting analysis could become an early tool for detecting dyslexia and dysgraphia in young children. The work, published in SN Computer Science, aims to improve current screening methods that are effective but often costly, time-consuming, and typically focus on only one condition at a time.
Implementation of Online Mindfulness With Peer Mentoring for Parent and Sibling Carers of People With Intellectual and Developmental Disabilities
Alcohol Consumption During Pregnancy and State Implementation of Legal Nonmedical Cannabis Retail Sales in the United States, 2011 to 2023
1National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia 2US Public Health Service Commissioned Corps, Rockville, Maryland 3Department of Economics, Finance, and Global Business, William Paterson University, Wayne, New Jersey 4Oak Ridge Institute for Science and Education (ORISE) Research Participation Program, Oak Ridge, Tennessee 5Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania...
Trends and Prevalence of Modifiable Risk Factors for Birth Defects Among U.S. Women of Reproductive Age: National Health and Nutrition Examination Survey 2007 to March 2020
INTRODUCTION Congenital heart defects (CHDs), orofacial clefts (OFCs), and neural tube defects (NTDs) are structural birth defects resulting from abnormalities during embryogenesis that can range in severity.1 These conditions are among some of the most common birth defects, with prevalence of about 100 per 10,000 live births for CHDs; 16 per 10,000 live births for OFCs; and 7 per 10,000 live births for NTDs in the U.S.2–4 The pathogenesis of these birth defects are multifactorial and...
CENTENE CORPORATION REPORTS SECOND QUARTER 2025 RESULTS 6:00 AM EDT 7/25/2025 - Comtex ST. LOUIS, July 25, 2025 /PRNewswire via COMTEX News Network/ -- Diluted Loss Per Share of $(0.51); Adjusted Diluted Loss Per Share of $(0.16) -- Centene Corporation (NYSE: CNC) (the Company) announced today its financial results for the second quarter ended June 30, 2025.
Digital Psychological Wellbeing Interventions for Family Carers of Children and Adults With Intellectual and Developmental Disabilities: A Systematic Review
People who care for their family member with intellectual and developmental disabilities can struggle with their mental health. Struggling with mental health includes feeling low or anxious. We wanted to find out what research has been done about online or virtual ways of helping family carers with their mental health. Online help can include websites and resources on the internet. Virtual help can include talking with a therapist through the internet.
Factors Associated With Length of Hospital Stay for Forensic Psychiatric Inpatients With Intellectual Disabilities
1 Introduction It is estimated that approximately 1.9% of the population of the United Kingdom has a diagnosed intellectual disability and this number appears to be increasing (Public Health England 2018). An intellectual disability is characterised by difficulties with intellectual and adaptive functioning which begins during childhood (Hughes-McCormack et al. 2017).
Prevalence of Intellectual and Developmental Disabilities in the US
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Overcoming Stuttering
By Amy Bamrick Stuttering is a communication disorder that affects fluency of speech. It is characterized by disruptions in which the flow of speech is broken by repetitions (li-li-like this), prolongations (lllllike this), or “blocks” in which the person has difficulty starting a word. Stuttering can impact quality of life greatly because it may cause a person to restrict their daily activities and interactions if they are concerned about others’ reactions to their speech.
CENTENE CORPORATION REPORTS FIRST QUARTER 2025 RESULTS 6:00 AM EDT 4/25/2025 - Comtex ST. LOUIS, April 25, 2025 /PRNewswire via COMTEX News Network/ -- Diluted EPS of $2.63; Adjusted Diluted EPS of $2.90 -- -- First quarter 2025 adjusted diluted EPS of $2.90, up 28% from $2.26 in the first quarter of 2024. -- 17% year-over-year premium and service revenue growth. -- Membership increases of 29% in Marketplace and 22% in Medicare PDP, compared to the first quarter of 2024.
Autism Has Different Faces and We Are One of Them!
by Annette Pinder Lyla Cardamone was 13 when she was finally diagnosed with autism. Now 14, she attends middle school, and loves art, reading, singing, girl-scouting, and is excited to be on the cover of Buffalo Healthy Living with her mom, Kelly Cardamone. The road to understanding why Lyla was different was long and confusing. “I had a normal pregnancy and birth, but we soon realized that Lyla had hypotonia, a medical condition characterized by decreased muscle tone, and weakness.
Prenatal Maternal Alcohol Exposure During the First Trimester of Pregnancy in Relation to Early Learning Ability, Behavioral Problems, and Autistic Traits in Preschool Children With or Without Autism Spectrum Disorder
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description aur70025-sup-0001-TableS1.docxWord 2007 document , 54 KB Table S1. Maternal alcohol drinking over time by case status. References 2013. “Child Behavior Checklist.” Burlington: Achenbach System of Empirically Based Assessment, Case Classification. American Academy of Pediatrics (AAP). 2024.
Ethics in Qualitative Research: Developing a Suicide Safety Protocol for Youth Facing Mental Health and Substance Use Challenges
STUDY PROTOCOL article Front. Psychiatry Sec.
What Are Developmental Disabilities?
The National Institutes of Health (NIH) explains that developmental disabilities are differences that are often present at birth that eventually affect a person’s physical, intellectual, and/or emotional development. A child with a developmental disability may begin to show signs prior to age 18, and result in differences in their ability to perform certain skills including learning, reasoning, and problem solving that affect their social and life skills.
Folate and Vitamin B12 Status among Non-Pregnant, Non-Lactating Women of Reproductive Age and Predicted Risk for Neural Tube Defects, Morogoro Region, Tanzania | Maternal and Child Health Journal
Abstract Population risk for neural tube defects (NTDs) can be determined using red blood cell (RBC) folate. However, a paucity of biomarker and surveillance data among non-lactating, non-pregnant women of reproductive age (NPWRA) from Africa limits accurate assessment. Our study assessed folate and vitamin B12 status among non-lactating NPWRA and predicted population risk of NTDs in Tanzania.
CENTENE CORPORATION REPORTS 2024 RESULTS 6:00 AM EST 2/04/2025 - Comtex ST. LOUIS, Feb. 4, 2025 /PRNewswire via COMTEX News Network/ -- 2024 Full Year Diluted EPS of $6.31; Adjusted Diluted EPS of $7.17 -- -- 2024 adjusted diluted EPS of $7.17, up 7% from $6.68 in 2023. -- Membership increases of 12% in Marketplace and 50% in Medicare PDP, compared to the fourth quarter of 2023. -- Executed on capital deployment with $3.0 billion of share repurchases in 2024.
Using ICD Codes Alone May Misclassify Overdoses Among Perinatal People
KEYWORDS pregnancy overdose ICD electronic health record medication for opioid use disorder Get full text access Log in, subscribe or purchase for full access. REFERENCES 1. Haight, SC ∙ Ko, JY ∙ Tong, VT ... Opioid use disorder documented at delivery hospitalization - United States, 1999-2014 MMWR Morb Mortal Wkly Rep. Aug 10 2018; 67:845-849 2. Ryan, KS ∙ Prewitt, KC ∙ Hayer, S ... Opioid use in pregnancy: a review Obstet Gynecol Surv. Jan 2023; 78:35-49 3.
COVID-19 Vaccine Reactogenicity Among Young Children
Introduction COVID-19 vaccine reactogenicity data among young children, which inform parental decisions and health care professional recommendations for vaccination, are limited. Reactogenicity can be described as expected and common symptoms after vaccination (eg, pain at injection site). We assessed reactions to COVID-19 vaccines among children of participants in the Centers for Disease Control and Prevention (CDC) COVID-19 Vaccine Pregnancy Registry (C19VPR).
Assessing Prenatal Alcohol Exposure History for Pediatric Patients: Practices Among U.S. Clinicians - Maternal and Child Health Journal
Abstract The American Academy of Pediatrics recommends clinicians who treat pediatric patients screen for prenatal alcohol exposure (PAE) to facilitate the identification of children with fetal alcohol spectrum disorders and promote timely access to behavioral and cognitive interventions. We evaluated how frequently clinicians inquire about PAE in their pediatric patient interactions and the methods used to ascertain this information.
The HYdrocortisone for Bronchopulmonary Dysplasia Respiratory and Developmental (HYBRiD) outcomes study: protocol for a longitudinal cohort study - BMC Pediatrics
All authors made substantial contributions to the design of the work and the acquisition, analysis, interpretation of data. All authors have read and approved the submitted version and have agreed to be personally accountable for their own contributions to the work.
Talk‐LD and Talk‐LD+: A pilot trial of school‐based interventions to challenge discrimination and promote inclusion
ATTID Attitudes Toward Intellectual Disability PSE Personal and Social Education RCT randomised control trial MRC Medical Research Council INTRODUCTION Young people with intellectual disabilities are significantly more vulnerable to bullying and victimisation than their peers, even when controlling for factors such as socioeconomic status (Naylor et al., 2012).
CENTENE CORPORATION REPORTS THIRD QUARTER 2024 RESULTS 6:00 AM EDT 10/25/2024 - Comtex ST. LOUIS, Oct. 25, 2024 /PRNewswire via COMTEX News Network/ -- Diluted EPS of $1.36; Adjusted Diluted EPS of $1.62 -- Reaffirms 2024 Adjusted Diluted EPS Guidance Floor of Greater Than $6.80-- -- Adjusted diluted EPS of $1.62 in the third quarter of 2024. -- Premium and service revenues of $36.9 billion in the third quarter of 2024.
Correction: Statistical analysis plan for the SOLUTIONS randomised controlled trial with internal pilot: Solution Focused Brief Therapy (SFBT) in 10-17-year-olds presenting at police custody | Trials | Full Text Original
Correction Open access Published: 13 October 2024 Trials volume 25, Article number: 675 (2024) Cite this article The Original Article was published on 28 September 2024 Correction: Trials 25, 633 (2024) https://doi.org/10.1186/s13063-024-08457-3 Following the publication of the original article [1], we were notified of a typo in the title.
Facts About Down Syndrome
The genes in the nuclei of cells in our chromosomes contain codes to all inherited traits, with each nucleus containing 23 pairs of chromosomes — half from one parent and half from the other. In Down syndrome, the nucleus contains a full or partial extra copy of chromosome 21. Trisomy 21. Down syndrome or trisomy 21 has 3, rather than 2 chromosomes in a pair. With 47 total chromosomes, the extra genetic material affects brain and body development and physical traits of Down syndrome. Risk Factors.
Promoting Growth at the People Inc. Greenhouse
By Roxane Albond-Buchner People Inc. provides opportunities for people with developmental disabilities to grow and learn while gaining independence. But People Inc.’s Brighton Day Park services and greenhouse program takes growth to a whole new level as participants engage with one another, plant, and learn in an environment filled with plants, trees, fruits, and vegetables.
Training an Anti-Ableist Physical Therapist Workforce: Critical Perspectives of Health Care Education that Contribute to Health Inequities for People with Disabilities
Americans with disabilities represent the largest historically underserved and marginalized health disparity population in the United States. This perspective piece will raise the awareness of physical therapy faculty and clinicians on gaps in health care provider knowledge about disability and provide actionable strategies, frameworks, and resources available to improve disability competence to make changes in clinical education and practice. In this perspective piece, 3 contributions are made.
Diurnal cortisol profiles in autistic adolescents and young adults: Associations with social difficulties and internalizing mental health symptoms
INTRODUCTION Autistic individuals are thought to experience increased daily-life stress and be exposed to various stressful life events (Hoover & Kaufman, 2018; van der Linden et al., 2021), which may be partly the result of several autism-related characteristics, including social difficulties, sensitivity to sensory information, or difficulties in emotion regulation (Kerns et al., 2015).
CENTENE CORPORATION REPORTS SECOND QUARTER 2024 RESULTS 6:00 AM EDT 7/26/2024 - Comtex ST. LOUIS, July 26, 2024 /PRNewswire via COMTEX News Network/ -- Diluted EPS of $2.16; Adjusted Diluted EPS of $2.42 -- -- Reaffirms 2024 Adjusted Diluted EPS Guidance Floor of Greater Than $6.80-- -- Adjusted diluted EPS of $2.42, up 15% from $2.10 in the second quarterof 2023. -- Premium and service revenues of $36.0 billion in the second quarter of 2024.
Dolutegravir- Versus Efavirenz-Based Treatment in Pregnancy: Impact on Red Blood Cell Folate Concentrations in Pregnant Women and Their Infants
In the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) 2010/VESTED study, pregnant women were randomized to initiate dolutegravir (DTG) + emtricitabine (FTC)/tenofovir alafenamide (TAF), DTG + FTC/tenofovir disoproxil fumarate (TDF), or efavirenz (EFV)/FTC/TDF. We assessed red blood cell (RBC) folate concentrations at maternal study entry and delivery, and infant birth.
Loneliness in daily life: A comparison between youths with autism spectrum disorders and 22q11.2 deletion syndrome (22q11DS)
INTRODUCTION Loneliness can be described as a negative emotional experience (Lay et al., 2019) but also as a gap between desires and reality in social relationships according to the social cognitive discrepancy theory (Plau & Perlman, 1982). Over the course of life, typically developing individuals (TD) encounter several periods of vulnerability to loneliness (Richard et al., 2017), adolescence being one of them (Danneel, Maes, Vanhalst, et al., 2018).
The potential use of artificial intelligence for venous thromboembolism prophylaxis and management: clinician and healthcare informatician perspectives | Scientific Reports
Abstract Venous thromboembolism (VTE) is the leading cause of preventable death in hospitalized patients. Artificial intelligence (AI) and machine learning (ML) can support guidelines recommending an individualized approach to risk assessment and prophylaxis. We conducted electronic surveys asking clinician and healthcare informaticians about their perspectives on AI/ML for VTE prevention and management.
Real World Data are Not Always Big Data: The Case for Primary Data Collection on Medication Use in Pregnancy in the Context of Birth Defects Research
Many examples of the use of real-world data in the area of pharmacoepidemiology include “big data” such as insurance claims, medical records, or hospital discharge databases. However, “big” is not always better, particularly when studying outcomes with narrow windows of etiologic relevance. Birth defects are one such outcome, where specificity of exposure timing is critical.
Real-world data are not always big data: the case for primary data collection on medication use in pregnancy in the context of birth defects research
Many examples of the use of real-world data in the area of pharmacoepidemiology include “big data,” such as insurance claims, medical records, or hospital discharge databases. However, “big” is not always better, particularly when studying outcomes with narrow windows of etiologic relevance. Birth defects are such an outcome, for which specificity of exposure timing is critical.
Celebrating Autism Acceptance Every Day
Courtesy of People Inc. There is no “one size fits all” when it comes to autism, and that is clear in the approach to the People Inc. day program on Hertel Avenue in Buffalo, where all participants fall somewhere on the autism spectrum. Whether it’s creating art, gardening, reading, volunteering, or learning daily living skills, each program attendee has a daily choice of activities and varied experiences.
A Tribute to My Son’s Teachers
By Laura Reilly When our son Jack was diagnosed with autism spectrum disorder, his diagnosis led us down a path we weren’t expecting. My husband and I were told he might never talk, and may require countless hours of treatment. We were living in Minnesota at the time, where agencies offering evidence-based therapy in an educational setting didn’t exist. Thankfully, a family member in Western New York mentioned The Summit Center.
Practitioners' experiences of delivering parenting interventions remotely: A mixed‐methods study
ADHD attention deficit hyperactivity disorder ASD autism spectrum disorder COVID-19 coronavirus disease GIF Graphics Interchange Format GSSTP Group Stepping Stones Triple P ID intellectual disability NHS National Health Service SSTP Stepping Stones Triple P UK United Kingdom INTRODUCTION Approximately, 40%–65% of children with intellectual disability (ID) display clinically significant internalising and externalising behavioural problems (Levy et al., 2010; Totsika et al., 2011).
Health Conditions, Education Services, and Transition Planning for Adolescents With Autism
Michelle M. Hughes, PhD National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia Address correspondence to Michelle M. Hughes, PhD, National Center on Birth Defects and Developmental Disabilities, U.S. Centers for Disease Control and Prevention (CDC), 4770 Buford Hwy, Atlanta, GA 30341.
Mental Health Care Utilization Among Parents of Children With Cancer
Key Points Question Are parents caring for children diagnosed with cancer more likely to utilize mental health (MH) services than other parents?
Annual health checks for people with intellectual disabilities: An exploration of experiences, follow‐up and self‐management of health conditions
Background Little is known about how health issues identified at the annual health check (AHC) are followed up and addressed, how participants self-manage their health in between AHCs, and what support they receive. This research aimed to explore this. Methods People with intellectual disabilities (n = 12), and/or their supporters residing in Wales, were interviewed following their AHC and again at 6 and 11 months. A recurrent cross-sectional thematic analysis was undertaken.
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