Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Articles by Dexiu Yan
Comparison of the Achieved and Expected Competence Level of New Graduate Nurses: Two Cross‐Sectional Studies
Aim To explore and compare the self-perceived competence level of new graduate nurses with the expected competence level that nurse managers believe new graduate nurses should have in general. Design Two cross-sectional empirical studies. Methods Two independent cross-sectional studies were carried out in 12 tertiary hospitals in September 2020 and November 2021, respectively.
Mechanisms of the influence of proactive personality on nurses' sense of social responsibility: A structural equation modelling study
Aim To explore the mechanism of proactive personality influence on nurses' sense of social responsibility through a serial multiple mediation model of volunteering motivation and self-efficacy. Design Further analysis of a cross-sectional and survey-based study. Methods In June 2023, a study was conducted with 722 Chinese nurses from four hospitals.
Global genome mining-driven discovery of an unusual biosynthetic logic for fungal polyketide-terpenoid hybrids
Global genome mining-driven discovery of an unusual biosynthetic logic for fungal polyketide–terpenoid hybrids Genome mining has facilitated the efficient discovery of untapped natural products. We performed global genome mining in fungi and discovered a series of biosynthetic gene clusters (BGCs) that appeared to afford polyketide–terpenoid hybrids via a distinct biosynthetic mechanism from those adopted by known pathways.
Biosynthetic Elucidation and Structural Revision of Brevione E: Characterization of the Key Dioxygenase for Pathway Branching from Setosusin Biosynthesis
Abstract Brevione E (1) is a fungal hexacyclic meroditerpenoid with unique oxepane and cycloheptenone moieties. In this study, we identified the biosynthetic gene cluster of 1 and elucidated its biosynthetic pathway via heterologous expression of the biosynthetic genes and in vitro enzymatic reactions. Surprisingly, reexamination of the structure of 1 revealed a substituted tetrahydrofuran ring instead of the previously proposed oxepane system.
Molecular and Computational Bases for Spirofuranone Formation in Setosusin Biosynthesis
The 3(2H)-furanone unit is observed in many biologically active natural products, as represented by the antifungal medication griseofulvin. Setosusin (1) is a fungal meroditerpenoid featuring a unique spiro-fused 3(2H)-furanone moiety; however, the biosynthetic basis for spirofuranone formation has not been investigated since its isolation.
Show More
loading
Actions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Dexiu
Contact Dexiu, search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck Rack