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Articles by Deyu Yi
Inside Back Cover: Subcellular Tandem-Activated Signal Amplification for Spatially Precise Molecular Imaging in Mitochondria
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Subcellular Tandem-Activated Signal Amplification for Spatially Precise Molecular Imaging in Mitochondria
1 Introduction Adenosine triphosphate (ATP) is the primary energy currency that powers essential cellular processes, including ion transport, macromolecule biosynthesis, and signal transduction [1, 2]. As the central hub of oxidative phosphorylation, mitochondria are responsible for generating over 90% of cellular ATP under aerobic conditions, underscoring their vital role in bioenergetics [3, 4].
Exogenously and Endogenously Sequential Regulation of DNA Nanodevices Enables Organelle‐Specific Signal Amplification in Subcellular ATP Profiling
Conflict of Interests The authors declare no conflict of interest. Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Inside Cover: Subcellular Compartment‐Specific Amplified Imaging of Metal Ions via Ribosomal RNA‐Regulated DNAzyme Sensors (Angew. Chem. Int. Ed. 4/2025)
Dr. Deyu Yi School of Chemistry and Biological Engineering Beijing Key Laboratory for Bioengineering and Sensing Technology, University of Science and Technology Beijing, 30 XueYuan Road, Beijing, 100083 China Search for more papers by this author
Subcellular Compartment‐Specific Amplified Imaging of Metal Ions via Ribosomal RNA‐Regulated DNAzyme Sensors
Conflict of Interests The authors declare no conflict of interest. Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Cover Picture: Modular Weaving DNAzyme in Skeleton of DNA Nanocages for Photoactivatable Catalytic Activity Regulation (Angew. Chem. Int. Ed. 18/2024)
Spatiotemporal control of catalytic DNAzyme activity has been achieved in the Research Article (e202404064) by Lele Li, Mengyuan Li et al. Molecular weaving activatable DNAzyme into the skeleton of tetrahedral DNA nanocages not only enables efficient intracellular delivery with improved biostability, but also allows for light-triggered on-demand liberation of DNAzyme and thus conditional control of catalytic gene regulation function.
Modular Weaving DNAzyme in Skeleton of DNA Nanocages for Photoactivatable Catalytic Activity Regulation
Conflict of interests The authors declare no conflict of interest. Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Frontispiece: A Remotely Controlled Nanosystem for Spatiotemporally Specific Gene Regulation and Combinational Tumor Therapy
Dr. Xin Chai CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing, 100190 China College of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beijing, 100049 China These authors contributed equally to this work. Search for more papers by this author
A Remotely Controlled Nanosystem for Spatiotemporally Specific Gene Regulation and Combinational Tumor Therapy
Graphical Abstract A NIR light-controlled, mitochondrial-targeted nanosystem achieves spatiotemporally selective gene regulation and tumor treatment. The system relies on photodynamic effect-induced translocation of a DNA repair enzyme, which enables spatially-controlled gene regulation and thus enhanced antitumor effects. Abstract The dearth of technologies that allow gene modulation and therapy with high spatiotemporal precision remains a bottleneck in biomedical research and applications.
Peptide Nucleic Acid (PNA)‐Guided Peptide Engineering of an Aptamer Sensor for Protease‐Triggered Molecular Imaging
Communication Dr. Zhichu Xiang, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing, 100190 China Search for more papers by this author Dr. Jian Zhao, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing, 100190 China College of Materials Science and...
Inside Back Cover: An Enzyme‐Activatable Engineered DNAzyme Sensor for Cell‐Selective Imaging of Metal Ions (Angew. Chem. Int. Ed. 12/2021)
Cover Picture Deyu Yi CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing, 100190 China College of Materials Science and Optoelectronic Technology, University of Chinese Academy of Sciences, Beijing, 100190 China These authors contributed equally to this work.
An Enzyme‐Activatable Engineered DNAzyme Sensor for Cell‐Selective Imaging of Metal Ions
Communication Deyu Yi CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing, 100190 China College of Materials Science and Optoelectronic Technology, University of Chinese Academy of Sciences, Beijing, 100190 China These authors contributed equally to this work.
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