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Articles by Diane C. Halstead
New study shows effectiveness of mpox vaccine
A new international study led by Queen Mary University of London has shown mpox (formerly known as monkeypox) infections to be less severe among those who are vaccinated or had a previous infection in 2022. The research, published in The Lancet Infectious Diseases, was delivered by the SHARE-net collaborative and looked at 38 mpox infections in 37 gay and bisexual men. Eight of the 38 were reinfections, and 30 infections occurred after a complete vaccination course.
SARS-CoV-2 infects coronary arteries, increases plaque inflammation
SARS-CoV-2, the virus that causes COVID-19, can directly infect the arteries of the heart and cause the fatty plaque inside arteries to become highly inflamed, increasing the risk of heart attack and stroke, according to a study funded by the National Institutes of Health.
World leaders commit to new targets to end TB
World leaders at the United Nations General Assembly’s High-Level Meeting on Tuberculosis have approved a Political Declaration with new targets for the next five years to advance the global efforts towards ending the TB epidemic.
CDC recommends new vaccine to help protect babies against severe respiratory syncytial virus (RSV) illness after birth
The Centers for Disease Control and Prevention (CDC) recommended the first respiratory syncytial virus (RSV) vaccine for pregnant people to protect their newborn from severe RSV illness. RSV is the leading cause of hospitalization for U.S. infants. This new vaccine, Pfizer’s bivalent RSVpreF vaccine (trade name Abrysvo), has been shown to reduce the risk of RSV hospitalization for babies by 57 percent in the first six months after birth.
Clinical trial to test immune modulation strategy for hospitalized COVID-19 patients begins
A clinical trial launched to test whether early intensive immune modulation for hospitalized COVID-19 patients with relatively mild illness is beneficial. The placebo-controlled study, part of the global clinical trials consortium known as Strategies and Treatments for Respiratory Infections and Viral Emergencies (STRIVE), will enroll approximately 1,500 people at research sites around the world.
Heart transplant patients from socioeconomically distressed communities face higher mortality, organ failure risk
People from socioeconomically distressed communities who underwent heart transplantation between 2004 and 2018 faced a 10% greater relative risk of experiencing graft failure and dying within five years compared to people from non-distressed communities, according to a study by UCLA researchers.
Infective endocarditis: Increased prevalence or improved diagnostics?
The incidence of infective endocarditis (IE), an infection of the heart endothelium, ranges between 5 to 7.9 cases per 100,000 individuals per year in the United States.1 If not diagnosed and treated promptly, organisms causing IE can damage or destroy heart valves leading to life-threatening complications and mortality.
T2Bacteria Panel: What you need to know
Diane C. Halstead In this guest editorial, Diane C. Halstead, PhD, DABMM, FAAM, who has over 35 years of experience as a clinical infectious disease laboratory director, discusses current data supporting T2 Biosystems’ T2Bacteria Panel, which patients should be tested using the technology, its potential economic benefits for both labs and hospitals, and how the test fits into a larger strategy to curb the use of inappropriate antibiotics.
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