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El carcinoma oral de células escamosas (COCE) representa más del 90 % de los casos de cáncer oral, y su detección temprana mejora significativamente el pronóstico. Sin embargo, la mayoría de los casos se diagnostica en etapas avanzadas. Los microARN (miARN), pequeñas moléculas de ARN no codificante que regulan procesos celulares clave, han surgido como biomarcadores salivales no invasivos con potencial para el diagnóstico precoz del COCE.
No matter what time of year it is, sneakers are always in season. So it should come as no surprise that adidas is here to lace the cool kids of spring with its latest line of shell toe Superstars. The brand with the three stripes created these classic leather kicks in 1970, and 50 years later they’re still a crucial part of street style and culture.
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