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Abstract Manual therapy is applied in the conservative management of sacroiliac joint (SIJ)-related symptoms, but whether its biomechanical effect is primarily related to joint mobilization or periarticular soft-tissue modulation remains unclear.
Abstract Introduction: This exploratory study aimed to characterize the differential features and intrinsic associations between peripheral proprioceptive deficits, aberrant quadriceps activation, and central sensorimotor network reorganization in patients with knee osteoarthritis (KOA). Methods: Twenty-eight outpatients with KOA and twenty-eight healthy controls (HC) were prospectively recruited between October 2024 and May 2025.
Abstract Background: Knee osteoarthritis (KOA) is a global public health crisis and a leading cause of disability among middle-aged and elderly populations. Historically characterized as a passive “wear-and-tear” process, the understanding of KOA has undergone a fundamental paradigm shift.
ORIGINAL RESEARCH article Volume 13 - 2025 | https://doi.org/10.3389/fbioe.2025.1735163 This article is part of the Research TopicBiomechanical Evaluation of Bone Structural Integrity: Experimental, Computational, and Clinical PerspectivesView all 3 articles Introduction Knee osteoarthritis (KOA) is a progressive disorder marked by a disparity between the degradation and regeneration of joint components (Hunter and Bierma-Zeinstra, 2019).
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