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Abstract Background: Intrahepatic cholangiocarcinoma (ICC) exhibits substantial cellular heterogeneity and a complex tumor microenvironment (TME), contributing to poor clinical outcomes. Effective prognostic biomarkers and a deeper understanding of the cellular ecosystems associated with high-risk disease remain urgently needed.
1 Introduction Hepatocellular carcinoma (HCC) is one of the most common malignancies, and its incidence has been rising worldwide.[1] Due to the inconspicuous symptoms of early HCC, most patients are diagnosed at an advanced stage and thus miss the best time for surgical treatment.
Abstract : With the growing global awareness of the environmental impact of clothing consumption, there has been a notable surge in the publication of journal articles dedicated to “fashion sustainability” in the past decade, specifically from 2010 to 2020. However, despite this wealth of research, many studies remain disconnected and fragmented due to varying research objectives, focuses, and approaches.
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