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Scientific Reports, Feb 2023 This is a preview of a remote PDF: https://www.nature.com/articles/s41598-023-28344-2.pdf Adhia, Divya Bharatkumar, Mani, Ramakrishnan, Mathew, Jerin, O’Leary, Finella, Smith, Mark, Vanneste, Sven, De Ridder, Dirk. , Scientific Reports, DOI: 10.1038/s41598-023-28344-2
Introduction Persistent pain is a significant presenting complaint in knee osteoarthritis (KOA), leading to activity limitation and participation restrictions (Vongsirinavarat et al., 2020). Available non-pharmacological and pharmacological interventions for reducing pain and improving function (Yusuf, 2016; Ferreira et al., 2019) only achieve modest improvements in pain outcomes and associated disability (Beswick et al., 2012; Kittelson et al., 2014; Gregori et al., 2018).
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