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D’Onofrio BM

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Articles by D’Onofrio BM

Genetic and environmental determinants of violence risk in psychotic disorders: a multivariate quantitative genetic study of 1.8 million Swedish twins and siblings

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By Geddes JR, Goodwin GM, D’Onofrio BM, Lahey BB
| Nature Verified
We report a population-based quantitative genetic study examining the aetiological links between psychotic disorders and violent crime using a sample of ~1.8 million Swedish individuals born between 1958 and 1989. Consistent with previous population-based research,11, 12, 13 we found substantial heritability estimates for schizophrenia, bipolar disorder, substance misuse and violent crime (h2=53–71%). Schizophrenia was a stronger predictor of violent crime (r=0.32) than bipolar disorder (r=0.23).
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Association of Labor Induction With Offspring Risk of Autism Spectrum Disorders

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By D’Onofrio BM, Rickert ME
| archpedi.jamanetwork.com
Importance  Induction of labor is a frequently performed obstetrical intervention. It would thus be of great concern if reported associations between labor induction and offspring risk of autism spectrum disorders (ASD) reflected causal influence. Objective  To assess the associations of labor induction with ASD, comparing differentially exposed relatives (siblings and cousins discordant for induction).
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