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Dörte Stalling

As seen in: Wiley Online Library
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Articles by Dörte Stalling

Live‐Cell RNA Imaging via Clickable TriPPPro Nucleotide Reporters

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By Eileen List, Dörte Stalling, J. Iven H. Knaack
| Wiley Online Library Verified
Introduction To gain a deeper understanding of cellular mechanisms, it is crucial to study biomolecules within their native cellular environment and elucidate their functions in biomolecular processes.
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A TriPPPro‐Nucleotide Reporter with Optimized Cell‐Permeable Dyes for Metabolic Labeling of Cellular and Viral DNA in Living Cells

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By Dörte Stalling, Timothy Soh, Jens B. Bosse, Vincente T. Sterrenberg
| Wiley Online Library Verified
Introduction Metabolic labeling of nucleic acids has been used since 1976, starting with 5-bromo-2′-deoxyuridine (BrdU).1 BrdU incorporates into newly synthesized DNA of dividing cells after being phosphorylated to its nucleoside triphosphate form (NTP) by endogenous kinases.
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A Triphosphate Pronucleotide (TriPPPro) Reporter with Optimized Cell‐Permeable Dyes for Metabolic Labeling of Cellular and Viral DNA in Living Cells

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By Chris Meier, Timothy Soh, Jens B. Bosse, Dörte Stalling
| pericles.pericles-prod.literatumonline.com
Abstract The metabolic labeling of nucleic acids in living cells is highly desirable to track the dynamics of nucleic acid metabolism in real-time and has the potential to provide novel insights into cellular biology as well as pathogen-host interactions. Catalyst-free inverse electron demand Diels-Alder reactions (iEDDA) with nucleosides carrying highly reactive moieties such as axial 2-trans-cyclooctene (2TCOa) would be an ideal tool to allow intracellular labeling of DNA.
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