01 How a Quality by Design framework guided scaling strategy and parameter selection across a five-run scale-down study in adherent AAV manufacturing 02 What batch-level data revealed when process parameters were compared between a 50 m² scale-down model and 500 m² manufacturing scale 03 How biomass capacitance enabled real-time detection of a seeding deviation before downstream impact Key interests AAV manufacturing Scale-down modelling Fixed-bed bioreactor Process comparability Quality by...