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Articles by E. Chong
BENDAMUSTINE LYMPHODEPLETION TRIGGERS REDUCED INFLAMMATORY CYTOKINES AND DECREASED TOXICITIES AFTER BOTH 4‐1BB‐ AND CD28‐COSTIMULATED CART19 FOR NON‐HODGKIN LYMPHOMA
Introduction: Lymphodepletion (LD) is a key component of anti-CD19 chimeric antigen receptor T cell (CART19) immunotherapy, establishing the proper environment and cytokine milieu before CART infusion. We previously demonstrated that Bendamustine (Benda) LD is as effective as standard fludarabine and cyclophosphamide (Flu/Cy) LD before the 4-1BB-costimulated tisagenlecleucel, but has reduced cytokine-release syndrome (CRS), neurotoxicity (ICANS), and hematological toxicities.
Outcomes with bendamustine lymphodepletion and brexucabtagene autoleucel for mantle cell lymphoma
Introduction: Brexucabtagene autoleucel (brexu-cel) is approved for relapsed/refractory mantle cell lymphoma (MCL). Cyclophosphamide/fludarabine for lymphodepletion (LD) is standard LD prior to brexu-cel. Due to a recent fludarabine shortage, we have utilized alternatives to fludarabine-based LD prior to brexu-cel, primarily bendamustine. We have previously reported our institutional experience with bendamustine LD prior to another anti-CD19 CAR T cell product.
FOURTH GENERATION HUCART19‐IL18 PRODUCES DURABLE RESPONSES IN LYMPHOMA PATIENTS PREVIOUSLY RELAPSED/REFRACTORY TO ANTI‐CD19 CAR T‐CELL THERAPY
Introduction: Lymphoma (NHL) patients (pts) relapsing/refractory (R/R) to anti-CD19 chimeric antigen receptor T-cells (CART) represent a challenging group in need of effective therapies. HuCART19-IL18 is a 4th generation 4-1BB CART product designed to express humanized anti-CD19 CAR and secrete interleukin 18, a pro-inflammatory cytokine shown to enhance CART efficacy in pre-clinical models.
Abstract No. 94 Extended 5-Year Amputation and Survival Outcomes from SINGAPACLI: A Randomized Clinical Trial Comparing Drug-Coated Balloon to Conventional Balloon Angioplasty for Below-the-Knee Arteries in Critical Limb Ischemia
The Singapore Infra-Genicular Angioplasty with Paclitaxel-eluting Balloon for Critical Limb Ischemia (SINGA-PACLI) trial is a randomized clinical trial comparing drug-coated balloon angioplasty (DCBA) to conventional (uncoated) percutaneous transluminal angioplasty (PTA) for below-the-knee (BTK) lesions in patients with chronic limb-threatening ischemia.
Boek | De Chinese kookkunst - E. Chong
Non-Fictie Uitgeverij Lantaarn Publishers Uitgegeven als Hardcover Eerste editie 01-10-1994 Laatste editie 01-10-1994 ISBN 9789054267829 Serie Koken in de wereld Taal Nederlands Populair in hetzelfde genre Boeken van dezelfde auteur Uitgelicht 2.5 Wat vind je van dit boek? Geef jouw beoordeling. 0 0 1 1 0 Willen dit boek lezen 0 Lezen dit boek 0 Hebben dit boek gelezen 2 De Nederlandse Boekenbon is supporter van lezerscommunity Hebban
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