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Effective systemic siRNA delivery using dual-layer protected long-circulating nanohydrogel containing inorganic core Yue Yin, Min Sang Lee, Jung Eun Lee, Su Yeon Lim, E Seul Kim, Jaeback Jung, Dahwun Kim, Jaeyun Kim, Doo Sung Lee and Ji Hoon Jeong Abstract Systemic delivery of small interfering RNA (siRNA) has been mainly impeded by enzymatic degradation and poor cellular uptake.
At 6 a.m. on a winter morning in Ridgewood, N.Y., a woman I’ll call Valia leaned on her kitchen counter, drinking black tea and packing a giant purse. She wore her blond-gray hair in a bun and pulled on an ankle-length brown puffer coat.
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