Follicular lymphoma (FL) is the commonest subtype of indolent lymphoma with approximately 1,860 new-cases diagnosed in the UK each year. The clinical management can range from immediate chemotherapy and/or radiotherapy through to simply observation (“watch-and-wait”), initiating treatment if/when symptoms develop. Previous studies have focussed on clinical trial data for specific drugs; meaning that their findings cannot be extrapolated to the general patient population.