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Objectives The use of genetically engineered enzymes in the synthesis of flavourings, fragrances and other applications has increased tremendously. There is, however, a paucity of data on sensitisation and/or allergy to the finished products.
Competing interests LTB, ES, PSB and XB declare that they have no financial or personal relationship with any organisation or person that would inappropriately influence their work or to have any other conflict of interest within 3?years of beginning the work submitted. ES had consultant arrangements with some of the companies whose workers have been tested within the study. XB and PSB testified in occupational litigation cases on behalf of plaintiffs.
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