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Editor, We read with great interest the study by Tsvetov [1] which has reported higher actual rates of denosumab-induced hypocalcaemia and recommend serum calcium monitoring in high-risk patients for early detection of severe hypocalcaemia. Denosumab is used in the treatment of osteoporosis in patients whom first-line agents are ineffective, poorly tolerated, or contraindicated such as in chronic kidney disease.
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