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1 Introduction The last two decades have seen an unprecedented rise of novel therapeutic approaches to treat cancer due to the growing understanding of cancer immunology and immunotherapy. These results contributed to turning into reality the paradigm that a patient’s immune cells may represent effective “living drugs” against cancer cells.
Abstract : There is an epidemic of obesity starting about 1980 in both developed and undeveloped countries definitely associated with multiple etiologies. About 670 million people worldwide are obese. The incidence of obesity has increased in all age groups, including children. Obesity causes numerous diseases and the interaction between genetic, metabolic, social, cultural and environmental factors are possible cofactors for the development of obesity.
3. Adenoviruses Adenoviruses are medium size viruses. All human adenoviral genomes have the same general organization. The genome consists of a single linear, double-stranded DNA molecule with short inverted terminal repeats at each end. A protein, terminal protein, is covalently attached to both the 5′ ends of the genomic DNA. The viral chromosome has five early transcription units (E1A, E1B, E2, E3 and E4) (Figure 1).
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