By Elizabeth Wells Updated December 29, 2014 Skip gallery slides Jamie Chung Statistics say you’ll catch two to four colds this winter. Here’s help to stave them off. Sleep Credit: Jamie Chung How it helps: Sleep regulates the release of the hormone cortisol, which stimulates cells that boost the immune system, says William Ellert, M.D., chief medical officer of the Phoenix Baptist Hospital. And a well-tuned immune system is crucial for defending against the cold virus.