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Ellen Lesser

As seen in: BioRxiv, eLife
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Articles by Ellen Lesser

Peripheral anatomy and central connectivity of proprioceptive sensory neurons in the Drosophila wing

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By Ellen Lesser, Anthony Moussa, John C. Tuthill
| eLife
eLife Assessment This important work describes wing mechanosensory neurons in detail, extending our understanding of sensorimotor processing in the fruit fly. The evidence presented convincingly supports the authors' identification of these neurons and leverages state-of-the-art methods to generate a near-complete map of wing mechanosensory circuitry. Overall, this study provides new hypotheses and invaluable tools for investigating proprioceptive motor control of the wing in Drosophila.
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Synaptic architecture of leg and wing premotor control networks in Drosophila

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By Ellen Lesser, Anthony W. Azevedo, Jasper S. Phelps, Leila Elabbady
| BioRxiv
Abstract Animal movement is controlled by motor neurons (MNs), which project out of the central nervous system to activate muscles. MN activity is coordinated by complex premotor networks that allow individual muscles to contribute to many different behaviors. Here, we use connectomics to analyze the wiring logic of premotor circuits controlling the Drosophila leg and wing. We find that both premotor networks cluster into modules that link MNs innervating muscles with related functions.
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Tools for comprehensive reconstruction and analysis of a female Drosophila ventral nerve cord

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By Anthony W. Azevedo, Ellen Lesser, Brandon Mark, Jasper S. Phelps
| BioRxiv
Abstract Like the vertebrate spinal cord, the insect ventral nerve cord (VNC) mediates limb sensation and motor control. Here, we apply automated tools for electron microscopy volume alignment, neuron segmentation, and synapse prediction toward creating a connectome of an adult female Drosophila VNC. To interpret a connectome, it is crucial to know its relationship with the rest of the body.
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Synaptic architecture of leg and wing motor control networks in Drosophila

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By Ellen Lesser, Anthony W. Azevedo, Jasper S. Phelps, Leila Elabbady
| BioRxiv
Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website.
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Tools for comprehensive reconstruction and analysis of Drosophila motor circuits

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By Anthony W. Azevedo, Brandon Mark, Jasper S. Phelps, Ellen Lesser
| BioRxiv
Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website.
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