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Cite This Article To the Editor: We were intrigued by Hernandez et al.’s recent important study linking persistent subjective symptoms after Lyme neuroborreliosis in Europe with increased interferon (IFN) α levels in blood (1). Their findings align with our earlier study in the United States, which showed an association between persistent objective neurocognitive deficits, despite antibiotic treatment for Lyme disease, and elevated blood IFN-α activity (2).
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